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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SCYL3 All Species: 27.88
Human Site: S391 Identified Species: 51.11
UniProt: Q8IZE3 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IZE3 NP_065156.5 742 82857 S391 G L R D T S D S I V A I T L H
Chimpanzee Pan troglodytes XP_513987 742 82925 S391 G L R D T S D S I V A I T L H
Rhesus Macaque Macaca mulatta XP_001096051 736 82375 S391 G L R D T S D S I V A I T L H
Dog Lupus familis XP_537198 743 82483 S391 G L R D T S D S I V A I T L H
Cat Felis silvestris
Mouse Mus musculus Q9DBQ7 735 81315 S391 G L R D T S N S I V A I T L R
Rat Rattus norvegicus Q5M9F8 807 89107 N425 K L S E T N L N V E L L K H F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514536 1518 163635 S1016 G L R D T N D S I V A I T L H
Chicken Gallus gallus NP_001012613 698 77220 T371 V V V G G E R T K I F K S S A
Frog Xenopus laevis Q561M0 827 91284 G482 F A P S R A A G V L G F A A T
Zebra Danio Brachydanio rerio NP_955951 768 85305 S392 G M R D T N D S L V A M T L Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610175 683 77833 L358 D A Q I R L I L L D Y F M D Y
Honey Bee Apis mellifera XP_001123124 613 70111 N289 K L K I F P E N I I A E Q L G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001177952 810 89574 N403 G L K D H H T N L V A D S L R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 95.1 85.5 N.A. 80.7 21.9 N.A. 31.8 61.9 21.8 51.9 N.A. 25.7 28.4 N.A. 33.5
Protein Similarity: 100 99.1 96.7 90.3 N.A. 87.7 38.5 N.A. 37.4 71.5 39 67.5 N.A. 45.9 49.7 N.A. 50.7
P-Site Identity: 100 100 100 100 N.A. 86.6 13.3 N.A. 93.3 0 0 66.6 N.A. 0 26.6 N.A. 40
P-Site Similarity: 100 100 100 100 N.A. 93.3 46.6 N.A. 100 26.6 20 93.3 N.A. 20 53.3 N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 16 0 0 0 8 8 0 0 0 70 0 8 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 62 0 0 47 0 0 8 0 8 0 8 0 % D
% Glu: 0 0 0 8 0 8 8 0 0 8 0 8 0 0 0 % E
% Phe: 8 0 0 0 8 0 0 0 0 0 8 16 0 0 8 % F
% Gly: 62 0 0 8 8 0 0 8 0 0 8 0 0 0 8 % G
% His: 0 0 0 0 8 8 0 0 0 0 0 0 0 8 39 % H
% Ile: 0 0 0 16 0 0 8 0 54 16 0 47 0 0 0 % I
% Lys: 16 0 16 0 0 0 0 0 8 0 0 8 8 0 0 % K
% Leu: 0 70 0 0 0 8 8 8 24 8 8 8 0 70 0 % L
% Met: 0 8 0 0 0 0 0 0 0 0 0 8 8 0 0 % M
% Asn: 0 0 0 0 0 24 8 24 0 0 0 0 0 0 0 % N
% Pro: 0 0 8 0 0 8 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 8 0 0 0 0 0 0 0 0 0 8 0 8 % Q
% Arg: 0 0 54 0 16 0 8 0 0 0 0 0 0 0 16 % R
% Ser: 0 0 8 8 0 39 0 54 0 0 0 0 16 8 0 % S
% Thr: 0 0 0 0 62 0 8 8 0 0 0 0 54 0 8 % T
% Val: 8 8 8 0 0 0 0 0 16 62 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _